One of the more common treatments for high blood pressure are ACE inhibitors. When your kidneys detect low blood pressure, they release an enzyme called renin, which stimulates the formation of a protein called angiotensin I. Angiotensin I is then converted by the angiotensin-converting enzyme (ACE) in the lungs to a very potent chemical called angiotensin II. Angiotensin II is a powerful blood vessel constrictor that causes muscles surrounding the blood vessels to contract, resulting in narrowing of the blood vessels. This narrowing of the vessels increases pressure in the vessels and can result in high blood pressure .
The ACE Inhibitors block the action of the angiotensin-converting enzyme in the lungs so that angiotensin I is not converted into angiotensin II. This allows blood vessels to remain widened, which results in lowering of the blood pressure. ARBs block the action of angiotensin II itself, so that vessels dilate, making it easier for the heart to pump blood, and results in lower blood pressure .
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